Single-dose & Repeated Dose Toxicity Testing

Prisys Biotech specializes in conducting repeated dose toxicity tests that provide robust safety testing data for drug development. These studies play a crucial role in informing key development decisions, and Prisys' experience in repeat dose toxicity supports data-driven decision-making. Prisys employs a team of toxicologists and clinicians who work together to design repeated dose toxicity studies. This design process considers available pharmacodynamic, pharmacokinetic, and toxicological information from previous studies, as well as the intended clinical use.

Repeated dose toxicity tests typically last between 2 to 6 weeks, and identifying biomarkers and other important translational endpoints during preclinical toxicology studies prior to clinical trials can reduce risk. Prisys' safety testing experts can collaborate with drug development teams to determine the general principles and designs of repeat dose toxicity tests. This includes species selection, treatment group size, duration of treatment, frequency, and route of administration, as well as relevant in-life observations and terminal endpoints based on the test article's properties and intended clinical use. Prisys also offers specialized endpoints based on the pharmacology of the test article through its toxicology laboratory services.

Populāri tagi: single-dose & repeated dose toxicity testing, China, research, study, monkey, gene therapy